Effect of Bitter Melon Extracts on Lipid Levels in Japanese Subjects: A Randomized Controlled Study

Table 2

Change in metabolic parameters after intervention with bitter melon.

		Control group (n = 20)	Intervention group (n = 23)	p-value
Body weight	Baseline	66.9 ± 14.5	62.5 ± 13.7	0.3
	Post intervention	66.6 ± 14.1	62.1 ± 13.5	0.3
	Change	-0.3 ± 1.1	-0.4 ± 1.2	0.6
Body mass index, kg/m^2	Baseline	24.0 ± 3.9	23.1 ± 4.6	0.5
	Post intervention	23.9 ± 3.7	22.9 ± 4.5	0.5
	Change	-0.1 ± 0.4	-0.2 ± 0.5	0.6
Systolic pressure, mmHg	Baseline	131.3 ± 20.2	131.3 ± 18.0	0.7
	Post intervention	130.7 ± 19.2	128.1 ± 22.7	0.7
	Change	-2.8 ± 14.7	-3.2 ± 14.6	0.9
Diastolic pressure, mmHg	Baseline	83.0 ± 15.3	81.2 ± 10.3	0.7
	Post intervention	83.3 ± 12.6	79.2 ± 11.3	0.3
	Change	0.3 ± 7.9	2.0 ± 8.7	0.4
Total cholesterol, mg/dL	Baseline	216.2 ± 34.5	224.3 ± 35.6	0.5
	Post intervention	220.8 ± 34.4	225.1 ± 38.8	0.7
	Change	4.6 ± 31.2	0.8 ± 19.1	0.6
LDL-C, mg/dL	Baseline	119.9 ± 28.7	129.0 ± 28.9	0.3
	Post intervention	131.9 ± 32.1	123.4 ± 32.0	0.4
	Change	12.0 ± 27.3	-5.7 ± 18.5	0.02
HDL-C, mg/dL	Baseline	68.3 ± 25.0	70.8 ± 19.4	0.7
	Post intervention	70.9 ± 20.2	69.6 ± 19.1	0.8
	Change	2.6 ± 15.6	-1.3 ± 8.4	0.3
Triglycerides, mg/dL	Baseline	116.5 ± 77.8	132.8 ± 108.4	0.3
	Post intervention	108.6 ± 61.6	192.1 ± 229.8	0.12
	Change	7.9 ±192.3	59.3 ± 200.4	0.17
Glucose, mg/dL	Baseline	111.8 ± 38.7	106.7 ± 38.4	0.7
	Post intervention	108.2 ± 34.3	108.2 ± 44.2	1.0
	Change	-3.6 ± 9.9	1.5 ± 12.3	0.15
Glycated hemoglobin, %	Baseline	5.9 ± 1.1	5.8 ± 1.1	0.8
	Post intervention	5.9 ± 1.0	5.8 ± 1.1	0.7
	Change	0 ± 0.1	0 ± 0.1	0.7