Simultaneous Quantification of Gallic Acid, Bergenin, Epicatechin, Epicatechin Gallate, Isoquercitrin, and Quercetin-3-Rhamnoside in Rat Plasma by LC-MS/MS Method and Its Application to Pharmacokinetics after Oral Administration of Ardisia japonica Extract

Table 1

MRM parameters of six compounds and three ISs.

Compounds	Q1	Q3	DP (V)	EP (V)	CE (V)	CXP (V)
Gallic acid	168.8	124.9	−28	−9	−20	−5
Bergeninum	327.0	191.9	−48	−8	−38	−5
Epicatechin	288.9	108.9	−45	−4.5	−35	−4
Epicatechin gallate	441.1	169.2	−55	−8	−28	−3.5
Isoquercitrin	462.9	300.0	−80	−8	−38	−6.5
Quercetin-3-rhamnoside	447.0	300.0	−60	−4.5	−35	−8
Ferulic acid (IS1)	192.8	134.1	−28	−9	−24	−5
Puerarin (IS2)	415.0	266.9	−62	−8	−45	−6.5
Warfarin (IS3)	307.0	161.1	−41	−9	−27	−7