Exploring the Pharmacological Mechanism of Danzhi Xiaoyao Powder on ER-Positive Breast Cancer by a Network Pharmacology Approach

<table class="fixed-width table-group" id="tab1"><tr><td><table class="table"><colgroup><col style="width:4.18em"/><col style="width:3.48em"/><col style="width:3.84em"/><col style="width:3.64em"/><col style="width:39.18em"/></colgroup><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Cluster</td><td class="align_center">Score</td><td class="align_center">Nodes</td><td class="align_center">Edges</td><td class="align_center">Genes</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">1</td><td class="align_center">17</td><td class="align_center">19</td><td class="align_center">153</td><td class="align_center">EIF4E, MTOR, EGFR, ERBB3, PIK3CA, SRC, PGR, IGF1, ESR1, CCND1, ERBB2, TP53, BCL2, FOXO3, JAK2, STAT5B, MYC, KDR, PTGS2</td></tr><tr><td class="align_left">2</td><td class="align_center">3</td><td class="align_center">7</td><td class="align_center">9</td><td class="align_center">FOXA1, RUNX1, NCOR2, GATA3, TFF1, EZH2, SIRT1</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Cluster of ER-positive breast cancer PPI network.</div>

Evidence-Based Complementary and Alternative Medicine

tab1

Table 1

Table 1: Exploring the Pharmacological Mechanism of Danzhi Xiaoyao Powder on ER-Positive Breast Cancer by a Network Pharmacology Approach 