A Validated LC-MS/MS Method for Simultaneous Determination of Six Aconitum Alkaloids and Seven Ginsenosides in Rat Plasma and Application to Pharmacokinetics of Shen-Fu Prescription

Table 2

Regression equations, correlation coefficients, linear ranges, and LLOQ of the 13 analytes.

Compounds	Regression equation	Correlation	Linear range	LLOQ
		coefficients(r)	(ng mL^−1)	(ng mL^−1)
AC	y=13.473763x+0.001605	0.9954	0.1-50.0	0.1
MA	y=9.925801x+0.000764	0.9967	0.1-50.0	0.1
HA	y=11.607255x+0.007185	0.9965	0.1-50.0	0.1
BAC	y=8.722507x+0.005974	0.9966	0.1-50.0	0.1
BMA	y=13.233070x+0.019068	0.9976	0.1-50.0	0.1
BHA	y=6.583533x+0.012468	0.9977	0.1-50.0	0.1
Rb1	y=0.417970x-0.001883	0.9980	1.0-500.0	1.0
Rb2	y=0.494477x-0.004015	0.9970	1.0-500.0	1.0
Rc	y=0.539509x-0.002736	0.9972	1.0-500.0	1.0
Rd	y=0.209590x-0.000697	0.9954	1.0-500.0	1.0
Re	y=0.247590x+0.000176	0.9953	1.0-500.0	1.0
Rf	y=0.232941x-0.002424	0.9975	1.0-500.0	1.0
Rg1	y=0.514582x+0.002851	0.9964	1.0-500.0	1.0