Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 4

Research Article

Syzygium jambos Displayed Antibacterial and Antibiotic-Modulating Activities against Resistant Phenotypes

Table 4

Preliminary antibiotic resistance modulatory activity of extracts at subinhibitory concentrations against S. aureus ST88 and P. aeruginosa PA124 strains.

Plant 
extracts and 
bacterial strains
Extract 
concentrations
Antibiotics, minimum inhibitory concentration (μg/mL), and fold increase (in brackets)
CHLTETCIPAMPCEFERYSTRKAN

S. aureus SA880256-2--3284
LeavesCMI/264 (4)32 (>4)1 (2)16 (>16)8 (>32)16 (2)4 (2)4 (1)
CMI/4128 (2)32 (>4)1 (2)256 (>2)32 (>8)64 (0.5)4 (2)4 (1)
CMI/8128 (2)-1 (2)256 (>2)-64 (0.5)4 (2)4 (1)
CMI/16128 (2)-1 (2)--64 (0.5)4 (2)4 (1)
BarkCMI/232 (8)64 (>2)≤0.5 (≥4)--4 (8)≤2 (≥4)4 (1)
CMI/432 (8)64 (>2)≤0.5 (≥4)--4 (8)≤2 (≥4)4 (1)
CMI/8128 (2)-1 (2)--32 (1)8 (1)4 (1)
CMI/16128 (2)-2 (1)--32 (1)16 (0.5)4 (1)
P. aeruginosa PA1240321616--326464
LeavesCMI/22 (16)1 (16)4 (4)--8 (4)16 (4)32 (2)
CMI/44 (8)1 (16)4 (2)--32 (1)32 (2)32 (2)
CMI/84 (8)4 (4)4 (2)--32 (1)32 (2)32 (2)
CMI/164 (8)4 (4)16 (1)--32 (1)32 (2)32 (2)
BarkCMI/232 (1)8 (2)4 (4)--16 (2)64 (1)16 (4)
CMI/432 (1)16 (1)4 (4)--16 (2)64 (1)32 (2)
CMI/832 (1)16 (1)4 (4)--16 (1)64 (1)64 (1)
CMI/1632 (1)16 (1)4 (4)--16 (1)64 (1)64 (1)

AMP: ampicillin, CEF: cefepime, CIP: ciprofloxacin, Ery: erythromycin, KAN: kanamycin; STR: streptomycin, TET: tetracycline; (-): >256 μg/mL; fold increase in bold: significant effect.