Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats

Figure 7

Effects of high-fat diet and EA on TNF-α expression. We found that the gene and protein expression of TNF-α significantly increased in Obesity group, P<0.001 versus Normal group. After EA or Resveratrol delivery, the increased level of TNF-α was modified, ###P<0.001, ##P<0.01, and #P<0.05 versus Obesity group. Resveratrol was more effective in regulation mRNA level of TNF-α than EA ($P<0.05 versus EA group), but there was no statistic difference in protein expression between EA and Resveratrol.