Danggui Sini Decoction Protected Islet Endothelial Cell Survival from Hypoxic Damage via PI3K/Akt/eNOS Pathway

<div>Phosphorylation of PI3K/Akt and eNOS was dose-dependently inhibited by CoCl<sub>2</sub> treatment. The cells were treated with different concentrations of CoCl<sub>2</sub> for 12 hours or 24 hours. Protein level of p-Akt was reduced in MST1 cells stimulated with CoCl<sub>2</sub> (a, b). Protein level of p-eNOS was reduced in MST1 cells stimulated with CoCl<sub>2</sub> (c, d). *<i>P </i>&lt; 0.05 versus control group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3

Figure 3: Danggui Sini Decoction Protected Islet Endothelial Cell Survival from Hypoxic Damage via PI3K/Akt/eNOS Pathway 