Danggui Sini Decoction Protected Islet Endothelial Cell Survival from Hypoxic Damage via PI3K/Akt/eNOS Pathway

<div>Effects of DSD on PI3K/Akt/eNOS signaling in CoCl2 treated MST1. (a-b) Representative Western blots of total and phosphorylated Akt protein expression. *P &lt; 0.05 versus vehicle group (V); #P &lt; 0.05 and ###P &lt; 0.001 versus CoCl2 + vehicle group (V); &amp;P &lt; 0.05 and &amp;&amp;P &lt; 0.01 versus CoCl2 + DSD group; (c-d) Representative Western blots of total and phosphorylated eNOS protein expression. *P &lt; 0.05 versus vehicle group (V); #P &lt; 0.05 and ###P &lt; 0.001 versus CoCl2 + vehicle group (V); &amp;P &lt; 0.05 and &amp;&amp;P &lt; 0.01 versus CoCl2 + DSD group.</div>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Danggui Sini Decoction Protected Islet Endothelial Cell Survival from Hypoxic Damage via PI3K/Akt/eNOS Pathway 