Effects of Chailong Jieyu Pill on Behavior, Monoamine Neurotransmitters, and Corticosteroid Receptors in a Rat Model of Anxiety Disorder

Table 3

Comparison of open-field test results at different time points in each group (mean ± SD, score, n = 40).

	Group	Before modeling	After modeling	After administration
Horizontal movement	Blank control	46.75±6.80	43.13±5.91	44.00±5.95
	Model	46.50±6.55	26.88±5.91	25.88±7.70
	Citalopram	47.63±11.51	27.63±7.23	35.13±8.60
	Low-dose Chailong Jieyu Pill	46.38±12.20	30.13±8.01	42.75±3.96^▲▲○
	High-dose Chailong Jieyu Pill	44.38±9.12	27.13±7.26	43.88±7.26^▲▲○
Vertical movement	Blank control	11.50±3.21	10.00±3.46	10.75±4.27
	Model	11.13±2.70	5.00±2.27	5.25±2.38
	Citalopram	10.88±4.36	5.75±3.11	6.88±2.30
	Low-dose Chailong Jieyu Pill	11.38±4.10	5.88±2.90	9.25±3.88^▲
	High-dose Chailong Jieyu Pill	0.88±3.09	5.75±3.92	9.75±2.76^▲▲○

P < 0.05, P < 0.01, versus blank control group; ^▲P < 0.05, ^▲▲P < 0.01, versus model group; ^○P < 0.05, versus citalopram group.