Metabolomics Analysis of the Lipid-Regulating Effect of Allium hookeri in a Hamster Model of High-Fat Diet-Induced Hyperlipidemia by UPLC/ESI-Q-TOF Mass Spectrometry

Table 2

Result from ingenuity pathway analysis with MetPA.

Pathway	Total	hits	p	-log(p)	Holm p	FDR	impact
Glycerophospholipid metabolism	39	2	0.0015041	6.4996	0.12033	0.12033	0.104
Linoleic acid metabolism	15	1	0.024711	3.7005	1.0	0.98842	0.000
alpha-Linolenic acid metabolism	29	1	0.047358	3.05	1.0	1.0	0.000
Primary bile acid biosynthesis	47	1	0.075893	2.5784	1.0	1.0	0.000
Arachidonic acid metabolism	62	1	0.099179	2.3108	1.0	1.0	0.000
Aminoacyl-tRNA biosynthesis	75	1	0.119	2.1286	1.0	1.0	0.000
Arginine and proline metabolism	77	1	0.12202	2.1036	1.0	1.0	0.102

The total is number of compounds in the pathway; the hits are the actually matched number from the user uploaded data; the raw p is the original p value calculated from the enrichment analysis; the Holm p is the p value adjusted by Holm-Bonferroni method; and the impact is the pathway impact value calculated from pathway topology analysis.