The Effects of the Honey-Roasting Process on the Pharmacokinetics of the Six Active Compounds of Licorice

Figure 1

Representative MRM chromatograms of LA, LQ, ILQ, LG, GA, and IS in plasma: (a) blank plasma; (b) a blank plasma sample spiked with LA (100.00 ng/mL), LQ (166.67 ng/mL), ILQ (40.00 ng/mL), LG (16.67 ng/mL), ILG (166.67 ng/mL), GA (5.00 ng/mL) reference standard, and IS (10.00 µg/mL); (c) and an actual plasma sample obtained from a rat at 2.5 h after oral administration of 25% honey-roasting licorice. 1 (LA), 2 (LQ), 3 (ILQ), 4 (LG), 5 (ILG), 6 (GA), 7 (IS).

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(b)

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