Effects of Methanol Fraction from Leaves of Schinus terebinthifolius Raddi on Nociception and Spinal-Cord Oxidative Biomarkers in Rats with Neuropathic Pain
Table 1
Antioxidant properties and chemical compounds of the fractions of Schinus terebinthifolius.
Schinus terebinthifolius fractions
Antioxidant standard
HeF
DcF
EtF
MeF
Scavenging activity against hydroxyl radical in IC50
59.09 ± 4.8
146.21 ± 6.8
32.57 ± 0.8
134.09 ± 7.0
BHT 46.21 ± 0.8
Scavenging activity against DPPH radical in IC50
596.2 ± 0.4
238.99 ± 0.2
5.19 ± 0.1
3.00 ± 0.1
BHT 6.25 ± 0.1 AA 2.43 ± 0.1
Total reactive antioxidant potential (TRAP)
2.5 g/mL
1.49 ± 0.1
2.32 ± 0.1
1.51 ± 0.1
3.22 ± 0.1
ND
5.0 g/mL
1.73 ± 0.1
2.39 ± 0.2
2.18 ± 0.1
4.02 ± 0.4
ND
10.0 g/mL
1.19 ± 0.1
2.42 ± 0.1
3.50 ± 0.2
4.90 ± 0.3
ND
25.0 g/mL
1.27 ± 0.1
2.63 ± 0.1
4.265 ± 0.1
5.805 ± 0.1
ND
Total phenol content
7.49 ± 1.0
32.27 ± 8.4
357.62 ± 19
406.35 ± 16.1
ND
Anthraquinones
+
+
+
+
Triterpenes/steroids
+
+
+
+
Phenolic compounds
+
+
+
+
Flavonoids
−
−
+
+
Saponins
−
−
+
+
Coumarins
−
−
−
+
Alkaloids
−
−
−
−
Values are expressed as mean ± S.E. Values with different superscript letters in the same row are significant different at . ND: not detected. The units are expressed as follows: TRAP (M trolox equivalents); DPPH and hydroxyl (g/mL); total phenol content (mg EGA/g fraction). +: present; −: absent.
