Research Article

Investigation into the Individualized Treatment of Traditional Chinese Medicine through a Series of N-of-1 Trials

Table 3

The comparison between the individualized decoction and control decoction based on the group data of the symptom scores, the 24-hour sputum volume, and the CAT scores from the 14 N-of-1 trials.

Control decoction 
Mean (SD)
Individualized decoction 
Mean (SD)
Mean difference 
(95% CI)
value

Symptom scores370.18 (0.10, 0.25)
24 h sputum volume (ml)37(7.00, 17.49, 32.41)#(5.50, 15.80, 34.84)#
CAT scores291.95 (1.04, 2.86)

values were the results of mixed effects model. data with nonnormal distribution were expressed in median (interquartile spacing) and calculated with paired Wilcoxon signed rank test. available.