Effects of Cinnamaldehyde on the Cell Wall of A. fumigatus and Its Application in Treating Mice with Invasive Pulmonary Aspergillosis

Table 2

Mycological efficacy of cinnamaldehyde in treating immunosuppressive mice with A. fumigatus infection (14 days).

Grouping	n	Microscopic examination of fungus		Fungal culture		Fungal clearance rate (%)
		Positive	Negative	Positive	Negative	Microscopy	Culture
Cinnamaldehyde group	30	6	24	6	24	80.00	80.00
Voriconazole group	30	10	20	10	20	67.70	66.70
Saline group	30	30	0	30	0	00.00	0.00
Model group	30	30	0	30	0	00.00	0.00
Immunosuppression group	30	0	30	0	30	0.00	0.00

The fungal clearance rates of the cinnamaldehyde and voriconazole groups were compared with those of the saline, model, and immunosuppression groups using SPSS21.0 statistical software (P < 0.01). However, a comparison between the cinnamaldehyde and voriconazole groups suggested a P value <0.05.