Therapeutic Effects of Kangzhi Syrup in a Guinea Pig Model of Ovalbumin-Induced Cough Variant Asthma

Table 1

Grade of fibrosis	Manifestations
0	Alveolar septa: no fibrotic burden at the most flimsy small fibers in some alveolar walls; Lung structure: normal lung
1	Alveolar septa: isolated gentle fibrotic changes (septum ≤ 3 × thicker than normal); Lung structure: alveoli partly enlarged and rarefied, but no fibrotic masses present
2	Alveolar septa: clearly fibrotic changes (septum > 3 × thicker than normal) with knot-like formation but not connected to each other; Lung structure: alveoli partly enlarged and rarefied, but no fibrotic masses
3	Alveolar septa: contiguous fibrotic walls (septum > 3 × thicker than normal) predominantly in whole microscopic field; Lung structure: alveoli partly enlarged and rarefied, but no fibrotic masses
4	Alveolar septa: variable; Lung structure: single fibrotic masses (≤10% of microscopic field)
5	Alveolar septa: variable; Lung structure: confluent fibrotic masses (>10% and ≤50% of microscopic field). Lung structure severely damaged but still preserved
6	Alveolar septa: variable, mostly not existent; Lung structure: large contiguous fibrotic masses (>50% of microscopic field). Lung architecture mostly not preserved
7	Alveolar septa: nonexistent; Lung structure: alveoli nearly obliterated with fibrous masses but still up to five air bubbles
8	Alveolar septa: nonexistent; Lung structure: microscopic field with complete obliteration with fibrotic masses