<i>Apocynum venetum</i> Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress

<div>Effect of AVLE on Bcl-2, Bax, cytochrome c, caspase-3, caspase-9, BDNF, and CREB protein expression in the hippocampus of CUMS rats. Representative images of immunoblots are shown in the upper panels. 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CON: control; CUMS: chronic unpredictable mild stress; AVLE:<i> Apocynum venetum</i> leaf extract (120 mg/kg).</div>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: <i>Apocynum venetum</i> Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress 

Figure 4 | Apocynum venetum Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress 