Zishenwan Decreases Kidney Damage in Recurrent Urinary Tract Infection through the Inhibition of Toll-Like Receptor 4 Signal

Figure 3

Serum containing Zishenwan protected rat bladder smooth muscle cells from LPS in vitro. (a) LPS (10μg/ml) decreased cell viability with time and serum containing Zishenwan rescued rat bladder smooth muscle cells in dose. (b, c) After treated with LPS (10μg/ml) 24 hours, significant apoptosis was induced in rat bladder smooth muscle cells, and the serum containing Zishenwan decreased apoptosis in a dose dependent manner. , p<0.05 compared with model group; , p<0.01 compared with model group.

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