Immunomodulatory Effects of Kuseonwangdogo-Based Mixed Herbal Formula Extracts on a Cyclophosphamide-Induced Immunosuppression Mouse Model

Table 5

Changes in the splenic cytokine contents in intact or CPA-induced immunosuppressive mice.

Groups	Cytokines
	Splenic cytokine contents (pg/ml)
	Tumor necrosis factor-α	Interleukin-1β	Interleukin-10
Controls
Intact
CPA
β-Glucan
MHFe
500 mg/kg
250 mg/kg
125 mg/kg

Values are expressed mean ± SD of eight mice, pg/ml; CPA: cyclophosphamide; MHFe: two-sweetener-excluded Kuseonwangdogo-based mixed herbal formula aqueous extracts; as compared with intact control mice by LSD test; and compared with CPA control mice by LSD test.