Research Article

Immunomodulatory Effects of Kuseonwangdogo-Based Mixed Herbal Formula Extracts on a Cyclophosphamide-Induced Immunosuppression Mouse Model

Table 6

Histomorphometrical analysis in intact or CPA-induced immunosuppressive mice.

ItemsGroups
ControlsMHFe
IntactCPAβ-glucan500 mg/kg250 mg/kg125 mg/kg

Thymus-thickness
 Total (μm)
 Cortex (μm)
Spleen-thickness
 Total (μm)
 Cortex (μm)
WP number (/mm2)
LN-thickness
 Total (μm)
 Cortex (μm)
Follicle number (/mm2)

Values are expressed mean ± SD of eight mice; CPA: cyclophosphamide; MHFe: two-sweetener-excluded Kuseonwangdogo-based mixed herbal formula aqueous extracts; WP: White pulp; LN: submandibular lymph node, left sides; and as compared with intact control mice by LSD test; and as compared with CPA control mice by LSD test; and as compared with intact control mice by MW test; as compared with CPA control mice by MW test.