A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model

<div>HypoGen model matched with the compounds. H-bond acceptor (green sphere), H-bond donor (pink sphere), hydrophobic (light blue sphere), and pi-interaction (orange sphere) could test and design. The distance (Å) between different pharmacophore spheres suggested the spatial distribution. (a) The match of the known best compound and pharmacophore; (b) test set molecule; (c) Candidate 1a; (d) Candidate 1b.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 7

Figure 7: A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model 

Figure 7 | A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model 