Research Article

Interspecies Anticancer and Antimicrobial Activities of Genus Solanum and Estimation of Rutin by Validated UPLC-PDA Method

Table 1

The estimated IC50 (μg/mL) values of ethanolic extracts of different species of genus Solanum.

Sample codeHepG2
(Liver)
HEK-293
(Kidney)
MCF-7
(Breast)

SSEE58.3 ± 4.6950.1 ± 4.1842.1± 3.74
SVEE69.4 ± 5.8796.3 ± 6.9871.1 ± 5.97
SCEE25.7 ± 1.3928.4 ± 1.4145.2 ± 1.95
SGEE58.2 ± 3.6167.2 ± 3.7949.3 ± 2.27
SIEE43.7 ± 2.0648.4 ± 2.1165.3 ± 4.68
SNEE20.4 ± 1.19103 ± 7.9830.1 ± 1.29
5-Fluorouracil3.1 ± 0.092.5 ± 0.073.7 ± 0.10

S. schimperianum (SSEE), S. villosum (SVEE), S. coagulans (SCEE), S. glabratum (SGEE), S. incanum (SIEE), and S. nigrum (SNEE).