Xihuang Pill Induces Apoptosis of Human Glioblastoma U-87 MG Cells via Targeting ROS-Mediated Akt/mTOR/FOXO1 Pathway

Figure 2

Inhibitory effects of XHP on the growth of U-87 MG cells. U-87 MG cells were treated with the indicated concentrations of XHP or PTX for 24h, (a) Morphological changes of cell confluence were observed under phase-contrast microscopy (× 200). (b) Cell viability was determined by CCK-8 assay. IC₅₀ of PTX on U-87 MG cells was 4.67 ± 0.07 µM after 24h treatment (n = 3, mean ± SD). P < 0.05, P < 0.01 significantly different from the control. P values were determined by Student’s t-test.

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