Gut Microbiota Play an Essential Role in the Antidiabetic Effects of Rhein

Figure 3

L-cell immunohistochemical staining in db/db mice. (a) Rhein-treated group, (b) control group, (c) antibiotics-treated group, and (d) rhein + antibiotics-treated group (magnification: 200x). Brown granules on behalf of GLP-1-positive staining. (e) The number of L-cells per HPF in the terminal ileum.

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