Suppressive Effect of Quercetin on Nitric Oxide Production from Nasal Epithelial Cells In Vitro

Figure 5

Influence of quercetin on STAT6 activation in HNEpCs after IL-4 stimulation in vitro. HNEpCs at 1 x 10⁵ cells/ml are cultured with 10.0 ng/ml of IL-4 for 12 hours in the presence and absence of various concentrations of quercetin. STAT6 activation is measured using ELISA, and the results are expressed as the mean optical density at 450 nm ± SE of the triplicate cultures. The experiments are performed twice with similar results. Med. alone: medium alone; IL-4: interleukin-4; HNEpCs: human nasal epithelial cells.