Curative Anti-Inflammatory Properties of Chinese Optimized Yinxieling Formula in Models of Parkinson’s Disease

Figure 3

The glial response in the PD mouse model treated with OYF. The representative IHC staining for Iba-1⁺ microglia (a) and GFAP⁺ astrocytes (b) in SNpc. Scale bar = 100or 50 μm. The quantitative percentage of area occupied by Iba-1⁺ cells (c) and GFAP⁺ cells (d) is shown in the indicated region of SNpc. (e-g) RT-PCR analysis of TNF-α, IL-1β, and IL-6 expression in mouse midbrain. For PCR, β-actin was used as an internal control. Data is depicted standard deviation. ^##P< 0.01 versus control group; P< 0.05 versus MPTP-treated group using one-way ANOVA with post hoc LSD t-test, n=6.

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