Curative Anti-Inflammatory Properties of Chinese Optimized Yinxieling Formula in Models of Parkinson’s Disease

Table 2

Profile 2 pathway enrichment.

	Pathway	DEGs genes with pathway annotation (105)	All genes with pathway annotation (7226)	P-value
1	Cytokine-cytokine receptor interaction	11 (12.79%)	264 (3.65%)	0.000270
2	Jak-STAT signaling pathway	8 (9.3%)	158 (2.19%)	0.000547
3	Complement and coagulation cascades	5 (5.81%)	88 (1.22%)	0.003837
4	Glycerolipid metabolism	4 (4.65%)	61 (0.84%)	0.005828
5	Galactose metabolism	3 (3.49%)	32 (0.44%)	0.006293
6	Pentose and glucuronate interconversions	3 (3.49%)	33 (0.46%)	0.006864
7	Cell adhesion molecules (CAMs)	6 (6.98%)	160 (2.21%)	0.011753
8	Steroid hormone biosynthesis	4 (4.65%)	85 (1.18%)	0.018248
9	Steroid biosynthesis	2 (2.33%)	19 (0.26%)	0.020996
10	Protein digestion and absorption	4 (4.65%)	90 (1.25%)	0.022026
11	VEGF signaling pathway	3 (3.49%)	58 (0.8%)	0.031408
12	alpha-Linolenic acid metabolism	2 (2.33%)	24 (0.33%)	0.032616
13	Ascorbate and aldarate metabolism	2 (2.33%)	26 (0.36%)	0.037825
14	Fc epsilon RI signaling pathway	3 (3.49%)	66 (0.91%)	0.043553
15	Leukocyte transendothelial migration	4 (4.65%)	114 (1.58%)	0.046522
16	Tight junction	5 (5.81%)	167 (2.31%)	0.048382
17	Thyroid hormone synthesis	3 (3.49%)	70 (0.97%)	0.050385
18	Adipocytokine signaling pathway	3 (3.49%)	71 (0.98%)	0.052170
19	Bile secretion	3 (3.49%)	71 (0.98%)	0.052170
20	Gastric acid secretion	3 (3.49%)	73 (1.01%)	0.055832