Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats

Figure 6

Photomicrographs of hematoxylin and eosin stained sections of the liver. (a) Normal control rats showing a normal liver with a hepatic lobule and a uniform pattern of polyhedral hepatocytes radiating from the central vein (CV) towards the periphery, (b) positive control-1 rats showing normal histological structure of the central vein (CV), (c) positive control-2 rats with surrounding hexagonal hepatocytes, and (d) negative control rats demonstrating a disrupted arrangement of hepatocytes around the CV and in the lobule (black arrows), degeneration of the hepatocytes at the peripheral area of the CV (green arrows), and congestion of the CV associated with inflammatory infiltrates (red arrows). (e and f) Groups CF + GL and CF + AP rats show a remarkable degree of preservation of the cellular arrangement with mild to moderate inflammatory infiltrates and congestion of the CV [magnification: 40x].

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