Research Article
Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats
Table 5
Semiquantitative scoring of the architectural changes following histopathological examination of the rat’s liver and kidney.
| Scoring parameters | Normal control | Positive control-1 | Positive control-2 | Negative control | CF + GL | CF + AP |
| | Liver |
| Degeneration of hepatocytes | 1 | 1 | 1 | 3 | 2 | 3 | Inflammatory cell infiltration | 1 | 1 | 1 | 2 | 1 | 3 | Vascular congestion | 1 | 1 | 1 | 3 | 2 | 1 | Edema | 1 | 1 | 1 | 2 | 2 | 2 | Mean ± SD | | | | | | |
| | Kidney |
| Degeneration of tubular epithelium | 1 | 1 | 1 | 2 | 1 | 2 | Vacuolization | 1 | 1 | 1 | 1 | 1 | 1 | Glomerular necrosis | 1 | 1 | 1 | 2 | 1 | 1 | Mean ± SD | | | | | | |
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Scoring was performed as follows: 1 = minimal (<1%), 2 = slight (1–25%), and 3 = moderate (26–50%).
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