Plants Used as Anticancer Agents in the Ethiopian Traditional Medical Practices: A Systematic Review

Table 4

Adverse/side effects, contraindication implicated, and possible antidote.

Family	MP (s) involved	Contraindication (if any)	Adverse effect(s); [possible antidote recommended] (if any)	Reference
Asteraceae	Vernonia Amygdalina,	Pregnant women	A headache and diarrhea	[50, 57]
Cucurbitaceae	Zehneria scabra	-	A headache, vomiting, and diarrhea [Taking shower]	[50, 57]
Euphorbiaceae	Croton macrostachyus	Pregnant women	A headache, vomiting, diarrhea, urination; [“TEFF  INJERA” and porridge are anecdotes]	[50, 57]
		-	Any; [milk whey as an antidote]	[58]
		Pregnant women	Nausea, vomiting and diarrhea	[59]
Fabaceae	Calpurnia aurea	-	headache	[57]
	Millettia ferruginea	Pregnant women	Nausea, vomiting and diarrhea	[59]
Lobeliaceae	Lobelia rhynchopetalum	-	Vomiting and diarrhea; [“SHIRO WOT” (sauce made of pulse grains) and powder of Linum usitatissimum infusion in water]	[60]
Menispermaceae	Stephania abyssinica	-	Any; [milk whey as an antidote]	[58]
Phytolaccaceae	Phytolacca dodecandra	Pregnant women	Overdosage would result in death	[53]
		Women at a child-bearing age	Could result in sterility in women	[46]
		-	Vomiting and diarrhea; [“SHIRO WOT” (sauce made of pulse grains) and powder of Linum usitatissimum infusion in water]	[60]
		Children and pregnant women	Vomiting and diarrhea; [milk and red “TEFF” PORRIDGE]	[50, 57]
		Pregnant women	Nausea, vomiting and diarrhea	[59]
Polygonaceae	Rumex nervosus	Children	Vomiting and diarrhea; [red “TEFF’ PORRIDGE]	[50, 57]
Ranunculaceae	Clematis hirsuta var. hirsuta	-	A headache, Sweating, and diarrhea	[50, 57]
Rosaceae	Hagenia abyssinica	-	A headache, vomiting, and diarrhea	[50, 57]
			[“SHIRO WOT” (sauce made of pulse grains) and powder of Linum usitatissimum infusion in water]	[60]