Supplementation of Stingless Bee Honey from Heterotrigona itama Improves Antiobesity Parameters in High-Fat Diet Induced Obese Rat Model
Table 2
A distribution of pre- and post-mean body weight, mean BMI, and percentage of body weight gain in each study group of induced-obese SD rats after daily administration of stingless bee honey (SBH) for a period of six weeks.
Groups
Mean Body Weight (g) ± SEM
Mean BMI ± SEM
Percentage of Body Weight Gain () ± SEM
Pre-intervention
Post-intervention
Pre-intervention
Post-intervention
Group 1 (ND)
350.6 ± 3.1
468.1 ± 3.6
0.62 ± 0.006
0.73 ± 0.009
33.58 ± 1.2
Group 2 (Obese rats; HFD)
411.6 ± 7.7
549.9 ± 11.7
0.72 ± 0.006
0.83 ± 0.013
33.73 ± 2.8
Group 3 (Obese rats; HFD+1000 mg/kg SBH)
443.6 ± 8.2
497.3 ± 19.2
0.72 ± 0.010
0.73 ± 0.019
11.98 ± 3.1
Group 4 (Obese rats; HFD+750 mg/kg SBH)
471.7 ± 5.1
460.3 ± 13.6
0.72 ± 0.007
0.69 ± 0.016
-2.30 ± 2.9
Group 5 (Obese rats; HFD+500 mg/kg SBH)
453.6 ± 2.6
504.3 ± 21.6
0.71 ± 0.006
0.73 ± 0.018
11.14 ± 4.6
Group 6 (Obese rats; HFD+ orlistat)
463.0 ± 5.5
405.9 ± 6.6
0.73 ± 0.008
0.65 ± 0.009
-12.36 ± 0.6
Results are presented as means ± SEM, n = 7. Values are statistically significant at p < 0.05. Note: significantly different compared to normal control rats (group 1); significantly different compared to control obese rats (group 2). ND: normal diet; HFD: high-fat diet; SBH: stingless bee honey.