Absorption Characteristics of Combination Medication of Realgar and Indigo Naturalis: In Vitro Transport across MDCK-MDR1 Cells and In Vivo Pharmacokinetics in Mice after Oral Administration

Table 2

Pharmacokinetic parameters of arsenic after oral administration of realgar and realgar-indigo naturalis.

Parameters	Unit	realgar	realgar+ indigo naturalis
	h	0.75	0.75
	μg L^−1	2472.41	1681.32
AUC(0-24)	h μg L^−1	18992.00	24057.60
AUC(0-∞)	h μg L^−1	22039.20	30343.00
	h	8.58	9.91
MRT	h	12.97	15.57
R/RI		1.47
AUC(0-24) R/RI		0.79
AUC(0-∞) R/RI		0.73