Baccharis trimera (Carqueja) Improves Metabolic and Redox Status in an Experimental Model of Type 1 Diabetes

Table 4

Determination of biochemical parameters after seven days of treatment with hydroethanolic extract of Baccharis trimera. C: control group; C600: treated control with 600 mg/Kg of extract; C1200: treated control with 1200 mg/Kg of extract; D: non treated diabetic group; D600: treated diabetic with 600 mg/Kg of extract; D1200: treated diabetic with 1200 mg/Kg of extract. Values are expressed as means ± SEM. The statistical analysis was performed between the groups: C x C600; C x C1200; C x D; D x D600; D x D1200. Different letters indicate statistically significant between the compared groups (p < 0.05).

Parameters	Experimental groups
	C	C600	C1200	D	D600	D1200
Triacylglycerol (mmol/L)	0.6 ± 0.05^b	0.5 ± 0.03^b	0.5 ± 0.02^b	1.04 ± 0.2^a	1.04 ± 0.1^a	1.1 ± 0.1^a
Total cholesterol (mmol/L)	1.6 ± 0.08	2.08 ± 0.2	1.9 ± 0.1	1.08 ± 0.2	1.9 ± 0.2	1.6 ± 0.07
HDL (mmol/L)	1.2 ± 0.1	1.1 ± 0.1	1.06 ± 0.09	0.9 ± 0.08	0.9 ± 0.1	0.8 ± 0.1
Urea (mmol/L)	9.6 ± 0.2^b	9.7 ± 0.3^b	8.3 ± 0.4^b	29.6 ± 1.6^a	28.7 ± 1.6^a	25.8 ± 2.06^a
Creatinine (mmol/L)	60.3 ± 2.9	62.3 ± 1.8	63.4 ± 3.9	72.5 ± 2.2	88.7 ± 4.01	73.9 ± 6.08
AST (U/mL)	107.1 ± 3.9^b	116.2 ± 4.9^b	113.2 ± 3.6^b	139.1 ± 4.6^a	113.1 ± 5.4^c	112.7 ± 6.9^d
ALT (U/mL)	46.7 ± 1.8^b	48.6 ± 2.3^b	50.2 ± 2.8^b	93.9 ± 6.3^a	86.2 ± 8.5^a	91.9 ± 8.3^a