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Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 6705871, 8 pages
https://doi.org/10.1155/2018/6705871
Research Article

Xiaoqinglong Decoction Attenuates Chronic Obstructive Pulmonary Disease in Rats via Inhibition of Autophagy

1Department of Integrated Traditional Chinese and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, China
2Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China

Correspondence should be addressed to Huanan Wang; moc.361@nhgnawxh

Received 31 July 2017; Revised 7 December 2017; Accepted 2 January 2018; Published 31 January 2018

Academic Editor: Subash C. Gupta

Copyright © 2018 Huanan Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. Ghorani, M. H. Boskabady, M. R. Khazdair, and M. Kianmeher, “Experimental animal models for COPD: a methodological review,” Tobacco Induced Diseases, vol. 15, no. 1, article no. 25, 2017. View at Publisher · View at Google Scholar · View at Scopus
  2. C. D. Mathers and D. Loncar, “Projections of global mortality and burden of disease from 2002 to 2030,” PLoS Medicine, vol. 3, no. 11, article e442, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. G. B. D. Disease, I. Injury, and C. Prevalence, “Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study,” The Lancet, vol. 388, no. 10053, pp. 1545–1602, 2016. View at Google Scholar
  4. P. J. Barnes, “Chronic obstructive pulmonary disease 12: new treatments for COPD,” Thorax, vol. 58, no. 9, pp. 803–808, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Decramer, W. Janssens, and M. Miravitlles, “Chronic obstructive pulmonary disease,” The Lancet, vol. 379, no. 9823, pp. 1341–1351, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. K. F. Rabe, S. Hurd, A. Anzueto et al., “Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary,” American Journal of Respiratory and Critical Care Medicine, vol. 176, no. 6, pp. 532–555, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. L. Galluzzi, E. H. Baehrecke, A. Ballabio et al., “Molecular definitions of autophagy and related processes,” EMBO Journal, vol. 36, no. 13, pp. 1811–1836, 2017. View at Publisher · View at Google Scholar
  8. K. Nakahira, M. A. P. Porras, and A. M. K. Choi, “Autophagy in pulmonary diseases,” American Journal of Respiratory and Critical Care Medicine, vol. 194, no. 10, pp. 1196–1207, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Yang, P. Li, S. Fu, E. S. Calay, and G. S. Hotamisligil, “Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance,” Cell Metabolism, vol. 11, no. 6, pp. 467–478, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. Z.-H. Chen, H. P. Kim, F. C. Sciurba et al., “Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease,” PLoS ONE, vol. 3, no. 10, Article ID e3316, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. X. Li, H. Yang, H. Sun et al., “Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 114, no. 45, pp. E9655–E9664, 2017. View at Publisher · View at Google Scholar
  12. C. Zhang, L. Feng, M. Li, C. Dong, and W. Zhang, “Effects of Xiaoqinglong decoction on gene expression profiles in a rat chronic obstructive pulmonary disease model,” Bioscience Trends, vol. 6, no. 5, pp. 262–269, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Geng, Z. Chen, H. Ren, X. Niu, X. Yu, and H. Yan, “Effects of an early intervention using human amniotic epithelial cells in a COPD rat model,” Pathology - Research and Practice, vol. 212, no. 11, pp. 1027–1033, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Weidberg, E. Shvets, and Z. Elazar, “Biogenesis and cargo selectivity of autophagosomes,” Annual Review of Biochemistry, vol. 80, pp. 125–156, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. I.-F. Wang, B.-S. Guo, Y.-C. Liu et al., “Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 109, no. 37, pp. 15024–15029, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Kundu and C. B. Thompson, “Autophagy: basic principles and relevance to disease,” Annual Review of Pathology: Mechanisms of Disease, vol. 3, pp. 427–455, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. Z.-H. Chen, H. C. Lam, Y. Jin et al., “Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 107, no. 44, pp. 18880–18885, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. K. H. Kim, H.-H. Song, K.-S. Ahn, S.-R. Oh, R. T. Sadikot, and M. Joo, “Ethanol extract of the tuber of Alisma orientale reduces the pathologic features in a chronic obstructive pulmonary disease mouse model,” Journal of Ethnopharmacology, vol. 188, pp. 21–30, 2016. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Lu, W.-J. Wang, Y.-Z. Song, and Z.-Q. Liang, “The protective mechanism of Schisandrin A in d-galactosamine-induced acute liver injury through activation of autophagy,” Pharmaceutical Biology, vol. 52, no. 10, pp. 1302–1307, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. V. V. Giridharan, R. A. Thandavarayan, S. Arumugam et al., “Schisandrin B ameliorates ICV-infused amyloid β induced oxidative stress and neuronal dysfunction through inhibiting RAGE/NF-κB/MAPK and Up-regulating HSP/beclin expression,” PLoS ONE, vol. 10, no. 11, Article ID e0142483, 2015. View at Publisher · View at Google Scholar · View at Scopus