Research Article
Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways
Table 1
Effect of the ethanol extract and fractions from Radix Glycyrrhiza on NO production in LPS/IFNγ-stimulated RAW264.7 cells. RAW264.7 cells were treated with extract (10, 100, 200 μg/ml), each fraction (10, 100, 200 μg/ml), and TFRG (20, 40, 60 μg/ml) for 24 h with LPS/IFNγ stimulation. Nitrite accumulation in the culture medium was determined by the Griess reaction. C: control (nontreatment) group; M: LPS/IFNγ-stimulated model group; EAA: ethanol extract with stimulation; PEF: petroleum ether extracted fraction with stimulation; EEF: ethyl acetate extracted fraction with stimulation. BF: n-butanol extracted fraction with stimulation; AF: aqueous extracted fraction with stimulation; TFRG: total flavonoids of RG with stimulation; L-NIL: L-NIL at 50 μM with stimulation. Values are presented as the mean ± SEM from three replicates. ## versus C group; versus M group; versus M group.
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