The Antitumor Effect of Xihuang Pill on Treg Cells Decreased in Tumor Microenvironment of 4T1 Breast Tumor-Bearing Mice by PI3K/AKT~AP-1 Signaling Pathway

<div>FCM detects the number of Treg cells by XHP on tumor microenvironment. (a) The results of FCM. Because Treg cells are a kind of lymphocyte that expressed CD4, CD25, and Foxp3 at the same time, in this experiment, we need to separate the single cell suspension of lymphoma for lymphocyte. After that, taking 2 × 10<sup>6</sup> lymphocytes of each mouse in each group and CD4 gating for flow cytometry, the upper right quadrant is the Treg cells. (b) XHP groups on the number of Treg cells in the tumor microenvironment.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: The Antitumor Effect of Xihuang Pill on Treg Cells Decreased in Tumor Microenvironment of 4T1 Breast Tumor-Bearing Mice by PI3K/AKT~AP-1 Signaling Pathway 

Figure 3 | The Antitumor Effect of Xihuang Pill on Treg Cells Decreased in Tumor Microenvironment of 4T1 Breast Tumor-Bearing Mice by PI3K/AKT~AP-1 Signaling Pathway 