Research Article
Tauroursodeoxycholic Acid Protects Nucleus Pulposus Cells from Compression-Induced Apoptosis and Necroptosis via Inhibiting Endoplasmic Reticulum Stress
Figure 7
TUDCA inhibits compression-induced ER stress. (a) The ER morphology of the control group and 0.5 mM TUDCA group observed by electron microscope photographs. (b) The Western blot results of ER-stress-related biomarkers p-PERK, p-eIF2α, and p-IRE1. (c), (d), and (e) show the quantitative analysis of expression level of ER-stress-related biomarkers p-PERK, p-eIF2α, and p-IRE1. Results are presented as the fold change in TUDCA-treated groups relative to that in DMSO group ( and versus DMSO control).
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