Curcumin Downregulates Human GM3 Synthase (hST3Gal V) Gene Expression with Autophagy Induction in Human Colon Carcinoma HCT116 Cells

<div><b>Effect of 3-MA on curcumin-induced hST3Gal V gene expression in HCT116 cells. </b>HCT116 cells were preincubated with or without 3-MA (10 mM) for 3 h and then incubated with curcumin (0, 30, 50 <i>μ</i>M) for 24 h. The hST3Gal V mRNA levels were analyzed by RT-PCR using the extracted total RNAs. The abundance of <i>β</i>-actin mRNA was also analyzed as an internal standard.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 7

Figure 7: Curcumin Downregulates Human GM3 Synthase (hST3Gal V) Gene Expression with Autophagy Induction in Human Colon Carcinoma HCT116 Cells 