Research Article

Evaluation of Analgesic and Anti-Inflammatory Activities of Water Extract of Galla Chinensis In Vivo Models

Table 3

Effects of Galla Chinensis on carrageenan-induced rat paw edema.

GroupsDose Carrageenan-induced rat paw edema M ± SD (% inhibition of paw volume)
1 h2 h3 h4 h5 h6 h

Control35.83 ± 13.4148.61 ± 10.2946.39 ± 13.3439.59 ± 7.4539.56 ± 107835.82 ± 7.26
Indomethacin2 mg/kg22.88 ± 1.8
(36.14)
22.55 ± 7.5
(53.61)
24.45 ± 11.0
(47.29)
26.76 ± 10.3
(32.41)
22.88 ± 1.8
(42.16)
21.17 ± 10.4
(40.90)
Galla Chinensis1 g/kg20.17 ± 9.4
(43.71)
27.19 ± 5.6
(44.07)
29.41 ± 3.99 
(36.60)
31.25 ± 8.20 
(21.07)
30.19 ± 8.04 
(23.69)
29.04 ± 6.48 
(18.93)
Galla Chinensis0.5 g/kg25.96 ± 13.12 
(27.55)
29.04 ± 6.4
(40.26)
30.13 ± 2.23 
(35.05)
30.63 ± 7.14 
(22.63)
31.17 ± 11.72 
(21.21)
29.94 ± 10.32 
(16.42)
Galla Chinensis0.25 g/kg33.38 ± 1.74 
(6.84)
42.90 ± 13.49 
(11.75)
39.88 ± 14.66 
(14.03)
34.61 ± 8.24 
(12.58)
34.51 ± 5.34 
(12.77)
35.64 ± 7.61 
(0.5)

The values are presented as mean ± standard deviation . The asterisk denotes the significance levels in comparison with the negative control: < 0.05.