Research Article

Osteomeles schwerinae Extract Prevents Diabetes-Induced Renal Injury in Spontaneously Diabetic Torii Rats

Figure 2

Effects of OSSC on the level of α-SMA and TGF-ß1 in renal tissue. Immunohistochemical staining of α-SMA (a) and TGF-ß1 (b). 400x magnification. α-SMA (c) and TGF-ß1 (d) expression levels in the renal tissue in each group. Experimental groups: NOR, normal rat; DM, SDT rat; OSSC-100, DM treated with OSSC (100 mg/kg); OSSC-250, DM treated with OSSC (250 mg/kg). All data are expressed as mean ± SEM values (). versus NOR; versus DM.
(a)
(b)
(c)
(d)