Tou Nong San Attenuates Inflammation in TNBS-IBD Model by Inhibiting NF-κB Signaling Pathway

Table 2

Macroscopic and histological scores. TNS reduced tissue damage of TNBS-induced colitis. The criteria of assessment are described in Materials and Methods. Values are presented as means ± SD ( = 10). Model group versus normal group: ^#P < 0.05; ^##P < 0.001; TNBS versus treated groups:    represents P < 0.05;   represents P < 0.01.

	Macroscopic damage; (Mean ± SD)	Histological scores
		Severity of inflammation and infiltration of immune cells; (Mean ± SD)	Inflammation extent; (Mean ± SD)	Crypt damage; (Mean ± SD)	Total; (Mean ± SD)
Normal group	0.1 ± 0.3	0.1 ± 0.3	0.1 ± 0.3	0 ± 0	0.2 ± 0.6
Model group	3.9 ± 0.54^##	2.3 ± 0.78^##	2.3 ± 0.78^##	1.6 ± 0.49^##	6.2 ± 1.53^##
TNS 3.3	3.6 ± 0.66	1.4 ± 0.5	1.4 ± 0.49	1.3 ± 0.64	4.1 ± 1.58
TNS 6.6	3 ± 0.63	1.2 ± 0.4	1.2 ± 0.4	1.1 ± 0.54	3.5 ± 1.28
TNS 13.2	2.8 ± 0.79	0.9 ± 1.2	0.9 ± 0.7	0.9 ± 0.7	2.7 ± 2.1