Research Article
GEPSI: A Gene Expression Profile Similarity-Based Identification Method of Bioactive Components in Traditional Chinese Medicine Formula
Table 1
Top ten small molecule drugs that have higher similarity scores with the gene expression profile of SWT.
| Cmap name | Mean | Enrichment | value | Percent nonnull | Group in DrugBank |
| Phenoxybenzamine | 0.955 | 1.000 | 0.00000 | 100 | Approved | Diethylstilbestrol | 0.703 | 0.983 | 0.00004 | 100 | Approved | Anisomycin | 0.695 | 0.990 | 0.00012 | 100 | Experimental | Equilin | 0.609 | 0.970 | 0.00004 | 100 | Approved | Digoxigenin | 0.609 | 0.950 | 0.00012 | 100 | Approved | Resveratrol | 0.413 | 0.855 | 0.00002 | 100 | Experimental/investigational | Estradiol | 0.389 | 0.774 | 0.00000 | 94 | Approved/investigational | Prochlorperazine | 0.376 | 0.674 | 0.00012 | 88 | Approved | Genistein | 0.352 | 0.686 | 0.00000 | 81 | Investigational | Thioridazine | 0.344 | 0.626 | 0.00004 | 72 | Approved |
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