Electroacupuncture Relieves Visceral Hypersensitivity by Inactivating Protease-Activated Receptor 2 in a Rat Model of Postinfectious Irritable Bowel Syndrome

<div><b>EA alleviates VH in the IP-IBS rat model</b>. (a) The minimal dose required to induce the lifting of the abdominal wall in each of the five experimental groups. (b) The minimal dose required to induce body arching in each of the five experimental groups. Data are expressed as mean ± SEM (n = 9 rats for C and M group, n=6 for M+EA, M+AP, and M+EA+AP group), and statistical significance was determined using one-way ANOVA followed by Tukey’s multiple comparison tests. The M group was administered with TNBS; the M + EA group was administered with both TNBS and EA; the M + AP group was administered with both TNBS and PAR2-AP; the M+AP+EA group was administered with TNBS, PAR2-AP, and EA.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Electroacupuncture Relieves Visceral Hypersensitivity by Inactivating Protease-Activated Receptor 2 in a Rat Model of Postinfectious Irritable Bowel Syndrome 

Figure 2 | Electroacupuncture Relieves Visceral Hypersensitivity by Inactivating Protease-Activated Receptor 2 in a Rat Model of Postinfectious Irritable Bowel Syndrome 