In Vitro Antidiabetic Effects of Isolated Triterpene Glycoside Fraction from Gymnema sylvestre

Table 3

IC₅₀ values for porcine α-amylase, yeast α-glucosidase, and mammalian α-glucosidase inhibitory potential of TG.

Enzymes	IC50 values for TG (µg/mL)	IC50 values for acarbose (µg/mL)
α-glucosidase (yeast source)	3.16 ± 0.05	6.14 ± 0.05
rat Intestinal α-glucosidase (sucrase)	74.07 ± 0.51	44.30 ± 0.73
rat Intestinal α-glucosidase (maltase)	5.69 ± 0.02	0.059 ± 0.05
porcine α-amylase	1.17 ± 0.24	0.18 ± 0.02

At different concentrations of TG IC₅₀ values for yeast α-glucosidase, sucrase, maltase, and porcine α amylase were studied. Values are expressed as mean± SD of three independent experiments made in duplicate.
Indicating the significant levels at p<0.05.