Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 6 / Research Article
Guzhi Zengsheng Zhitongwan, a Traditional Chinese Medicinal Formulation, Stimulates Chondrocyte Proliferation through Control of Multiple Genes Involved in Chondrocyte Proliferation and Differentiation Table 6 Gene expression levels of growth plate chondrocyte markers.
Gene name Blank GZZSZTW log2 fold change (GZZSZTW /Blank) p value Fibroblast growth factor receptor 3 (Fgfr3) 57.13 97.35 0.77 2.34E-80 Cartilage matrix protein (Matn1) 102.96 124.45 0.27 1.06E-08 Cartilage oligomeric matrix protein (Comp) 712.93 775.11 0.12 1.77E-13 Protein patched homolog 1 (Ptch1) 3.92 5.44 0.47 2.92E-03 Runt-related transcription factor 2 (Runx2) 7.43 10.01 0.43 3.02E-05 Runt-related transcription factor 3 (Runx3) 4.68 6.26 0.42 7.23E-03 Parathyroid hormone/parathyroid hormone-related peptide receptor (Pth1r) 55.23 54.53 -0.02 8.96E-01 Transcription factor Sp7 (Sp7) 3.76 4.04 0.10 4.23E-01 Indian hedgehog protein (Ihh) 0.57 0.51 -0.16 4.99E-01 Collagen alpha-1(X) (Col10a1) 92.05 122.37 0.41 1.71E-25 Bone morphogenetic protein 6 (Bmp6) 4.38 5.37 0.29 1.19E-01 Bone sialoprotein 2 (Ibsp) 78.3 72.73 -0.11 1.04E-01
