Review Article

Potential of Mushroom Compounds as Immunomodulators in Cancer Immunotherapy: A Review

Table 1

Bioactive compounds from mushrooms with anticancer activity.

Mushroom Cancer Common name Compound/extract

Agaricus bisporus Breast, colorectalWhite buttonPolysaccharides, lectin
Ganoderma lucidum Breast, colorectal, cervical, prostate, liver, and lungLingzhi/reishiGanoderma polysaccharides, polysaccharide-peptides
Coriolus versicolorBreast, colorectal, and skinYun ZhiKrestin, PSK, PSP
Lentinus edodesCervical/ovarian, gastric, and skinShiitakeLentinan
Grifola frondosaBreast and bladderMaitakeGrifolan, Maitake D fraction
Agaricus blazeiLeukemia, hematological, stomach, and lungBrazilianAgaricus polysaccharides
P. tuber-regiumLiverKing tuberPleuran
Flammulina velutipes SkinWinterFlammulin

Modified from Roupas et al. (2012).