The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway

Figure 2

Treatment of different concentration of GJ extracts 7 days prior to MCAO promoted astrocyte proliferation of the ischemic cortex 24 h after reperfusion. (a) Activation of astrocyte was examined with specific antibody against GFAP (red); nuclei were stained with DAPI (blue) (magnification×400). (b) Statistical analysis was shown; data are demonstrated as the mean ± SEM. <0.01, versus sham group; p<0.01, p<0.05 versus I/R group. Scale bar 20 μm.

(a)

(b)