The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway

Figure 3

Treatment of different concentration of GJ extracts 7 days prior to MCAO increased the activity of neurons of the ischemic cortex in rat 24 h after reperfusion. Nissl staining was used to identify Nissl bodies at the ischemic cortex after 24 h of reperfusion. (a) Representative images magnified 100 times are shown. (b) Representative images magnified 400 times are shown. (c) Quantitatively analyzed Nissl bodies in the ischemic cortex in each group after 24 h of reperfusion. Data are means ± SEM. <0.01 versus sham group; p<0.01, p<0.05 versus I/R group. Scale bar 20 μm.

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