Effects of Juglans regia Root Bark Extract on Platelet Aggregation, Bleeding Time, and Plasmatic Coagulation: In Vitro and Ex Vivo Experiments

Table 1

Effect of the CAE of Juglans regia on APTT, PT, and TT and fibrinogen concentration.

Sample	Doses	PT (s)	APTT (s)	TT (s)	Fibrinogen (g/l)
Control	(1:1/v,v)	16.62 ± 1.16	13.96 ± 0.57	43.29 ± 2.20	1.17 ± 0.09
Juglans regia (mg/ml)	0.25	20.12 ± 1.13	19.74 ± 1.27	69.5 ± 1.67	0.68 ± 0.05
	0.5	19.62 ± 1.53	19.18 ± 1.55	80.24 ± 3.21	0.64 ± 0.04
	1	20.55 ± 0.76	25.06 ± 3.54	190.8 ± 11.63	0.49 ± 0.02
Heparin (U/ml)	0.4	53.48 ±	>300	>300	0.53 ± 0.03

Mean ± SEM, PT: prothrombin time, APTT: activated partial thromboplastin time, TT: thrombin time, p <0.05, p <0.01, p<0.001, and NS: no significant. n =5