Effects of Juglans regia Root Bark Extract on Platelet Aggregation, Bleeding Time, and Plasmatic Coagulation: In Vitro and Ex Vivo Experiments

Table 2

Effect of CAE of Jr on ex vivo on PT, APTT, and TT and fibrinogen concentration.

Sample	Doses	PT (s)	APTT (s)	TT (s)	Fibrinogen (g/l)
Distilled water (ml/100g)	1	18.26 ± 1.51	16.40 ± 1.46	39.62 ± 7.39	2.58 ± 0.07
CAE of Jr (mg/Kg)	250	20.94 ± 0.39	17.48 ± 1.81	54.96 ± 3.46	1.98 ± 0.10
Warfarin (mg/Kg)	1	33.30 ± 3.44	36.94 ± 3.06	117.96± 10.27	1.55 ± 0.06

Mean ± SEM, p < 0.01, p < 0.001, NS: not significant, and n = 5.