Time-, Sex-, and Dose-Dependent Alterations of the Gut Microbiota by Consumption of Dietary Daikenchuto (TU-100)

Figure 7

Dose-Dependent Chronological Changes of Fecal Microbiotas by TU-100. Fecal microbiotas were analyzed every 4 weeks from weeks 0 to 24. PCoA plots of unweighted UniFrac distances and weighted UniFrac distances over time are shown. Small dots represent individual samples and large spheroids represent means of each group. Red, blue, orange, green, and purple dots/spheroids are for group 1 (fed AIN-76A for 24 weeks), group 2 (fed 0.75% TU-100 for 12 weeks and then AIN-76-A for 12 weeks), group 3 (fed 0.75% for 24 weeks), group 4 (fed 3.0% TU-100 for 12 weeks and then AIN-76-A for 12 weeks), and group 5 (fed 3.0% for 24 weeks), respectively.